Description

Mycotrans 500 Tablet contains Mycophenolate Mofetil 500 mg, an immunosuppressant medicine manufactured by Healing Pharma. It is primarily prescribed in combination with other immunosuppressive medicines to help prevent the body’s immune system from rejecting a transplanted kidney, heart, or liver. Mycophenolate mofetil works by reducing the activity and multiplication of certain immune cells involved in transplant rejection.

Composition

Each Mycotrans 500 Tablet contains:

• Active ingredient: Mycophenolate Mofetil IP
• Strength: 500 mg
• Dosage form: Tablet
• Route: Oral
• Drug class: Immunosuppressant / antimetabolite
• Common pack: 1 × 10 tablets, although pack sizes may vary.

Uses of Mycotrans 500

Mycotrans 500 is used with other immunosuppressive medicines to prevent organ rejection following transplantation. Its established transplant-related uses include:

• Kidney transplant
• Heart transplant
• Liver transplant

It helps reduce the immune response against the transplanted organ, allowing the body to accept the new organ.

Mechanism of Action

Mycotrans 500 contains mycophenolate mofetil, which is converted in the body to mycophenolic acid. It inhibits inosine monophosphate dehydrogenase (IMPDH), an enzyme needed for the production of guanine nucleotides.

This particularly affects the proliferation of T and B lymphocytes, reducing the immune response that can contribute to rejection of a transplanted organ.

Dosage and Administration

The dose of Mycotrans 500 is individualized according to the type of transplant, other immunosuppressive medicines being used, kidney function and the patient’s clinical condition.

Take Mycotrans 500 exactly as prescribed by your transplant specialist. Do not change the dose or stop treatment even if you feel well, because stopping immunosuppressive treatment can increase the risk of organ rejection.

Swallow the tablet whole with water. Do not crush, chew or break it unless specifically instructed by your healthcare professional. Some product information recommends taking mycophenolate on an empty stomach—approximately 1 hour before or 2 hours after food—while your transplant team may provide individualized instructions. Follow the instructions given by your prescriber.

Possible Side Effects

Common or clinically important adverse effects may include:

• Nausea
• Vomiting
• Diarrhea
• Abdominal discomfort
• Headache
• Dizziness
• Fatigue or weakness
• Insomnia
• Tremors
• Increased risk of bacterial, viral and fungal infections
• Anemia
• Reduced white blood cell count
• Reduced platelet count
• Changes in liver or kidney laboratory values

Contact your healthcare team promptly if you develop fever, persistent sore throat, unusual bruising or bleeding, severe diarrhea, or other signs of infection